The findings further emphasize the role of local factors in generating polymorphisms in the T-cell epitopes of the P. falciparum circumsporozoite protein.”
“Polyurethane

dispersions (PUDs) have been designed and synthesized based on different types of soft segments, namely, poly(2,4-diethyl-1,5-pentamethylene adipate) glycol (PDPAD; (M(n)) over bar = 1000) and poly(2,4-diethyl-1,5-pentamethylene-1,4-cyclohexane dicarboxylate) glycol (PDPCD; 1000), and were subsequently modified with fluoro oligomer (BA-N fluoroalcohol). It was found that the PDPCD segments improved the hydrolytic stability, whereas the contact angle with water drop was significantly increased with the addition and increasing amount of Zonyl for PDPAD-based PU and it was marginally increased with PDPCD-based PU. In addition, the PDPCD provided PUD with enhanced mechanical properties compared with the PDPAD. (C) www.selleckchem.com/products/PD-173074.html 2008 Wiley Periodicals,

Inc. J Appl Polym Sci 111: 1828-1834, 2009″
“Perfluoroalkyl acids (PFAAs) are a group of chemicals used for many applications and widely present in the environment and humans. In this study, serum levels of PFAAs and isomers of perfluorooctanesulfonate GSK2399872A datasheet (PFOS) and perfluorooctanoate (PFOA) were analyzed in 141 Chinese pregnant women. Among all the samples, total PFOS (Sigma PFOS, mean concentration 732 ng/mL) was predominant, followed by Sigma PFOA (mean 4.78 ng/mL) and perfluorodecanoate (PFDA, mean 1.45 ng/mL). On average, the proportion of linear PFOS (n-PFOS) was 66.7% of Sigma PFOS, which was

higher than the general population, implying that maternal women could excrete branched PFOS isomers to the fetus by transplacental transfer. Moreover, the proportion of n-PFOS decreased significantly with the increasing concentration of Sigma PFOS in the serum samples (r = 0342,p < 0.001). The mean proportion selleck screening library of n-PFOA in the serum samples was 99.0%, which was much higher than the technical ECF (electrochemical fluorination) products (ca. 70%). The small proportion of branched isomers of PFOA suggests that there is still a source of ECF PFOA in China. Significant correlations (p < 0.005) were observed between the concentrations of some PFAAs with certain medical parameters in the pregnant women. For example, the levels of most perfluorinated carboxylic acids (PFCAs) were found to correlate with albumin significantly, which might be a sign of immunotoxicity of these chemicals. The adverse effects of PFAA exposure to pregnant women may increase the health risk of the fetus. Interestingly, not only the PFAA concentrations but also the percentages of PFOS and PFOA isomers were correlated with certain medical parameters. This implies that the compositions of PFOS or PFOA should be considered in human health risk assessment in the future. (C) 2013 Elsevier Ltd. All rights reserved.