The

0.8 mu m thick films exhibit strong enhancement of the critical current density, reaching a maximum of 4.2 MA/cm(2) at 77 K. The result emphasizes the critical role of catalysis for synthesis of novel complex materials. (C) 2010 American Institute of Physics. [doi: 10.1063/1.3517467]“
“Tumor-induced osteomalacia (TIO) is a rare acquired paraneoplastic disease characterized by renal phosphate wasting and hypophosphatemia. Recently, it was reported that tumors associated with TIO produce fibroblast growth factor (FGF) 23, identified as the last member PDGFR inhibitor of the FGF family and of which excessive action causes several hypophosphatemic diseases whereas deficient FGF23 activity results in hyperphosphatemic tumoral calcinosis. In this case, although it was difficult to locate the associated tumor, an abnormal mass in the left maxilla was detected by imaging. The tumor was removed by partial resection of the left maxillary alveolar region. Thereafter, serum level of FGF23 rapidly decreased, hypophosphatemia improved, and the clinical symptoms greatly improved. Histopathologic diagnosis of the tumor was phosphaturic mesenchymal tumor, mixed connective tissue variant. Immunohistochemical findings confirmed that the removed tumor produced FGF23. These results indicate that development of osteomalacia in this patient was related to the maxillary tumor, which overexpressed

Momelotinib in vivo FGF23. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010; 109: e57-e63)”
“The development of metallocene-based catalysts is an important advance on the study of polyolefinic materials. However, due to the rather different www.selleckchem.com/products/DAPT-GSI-IX.html conditions that are established in actual applications, only around 3% of these polymers are obtained from metallocene technology. In view of this, novel strategies must be developed to produce metallocene-based catalysts that are more thermally stable, which is a fundamental requirement to establish metallocene technologies.

Homogeneous and heterogeneous polymerizations of ethylene were compared, using the Ph2C(Cp)(Flu)ZrCl2/MAO system. Homogeneous polymerizations were more active than the corresponding supported reactions. At low ethylene pressure, the addition of 1-hexene increases the activity under homogeneous conditions. Nevertheless, this is not observed on the respective supported systems. At higher pressure conditions, all polymerizations attained higher yields. However, when the reaction temperature increases the activity significantly decreases under homogeneous conditions. Furthermore, when the polymerization was performed under heterogeneous conditions the deactivation was lower. The homogeneous and supported catalytic systems show different characteristics and, in all attempted reactions, immobilization of the molecular catalyst reduces the activity. However, the deactivation ratio was lower when the polymerization was performed under heterogeneous conditions.