Patients who had radiotherapy also benefited from CI, but their outcomes were variable.”
“Purpose: To translate the English version of the Quality of Life-Rheumatoid Arthritis Scale (QOL-RA Scale) into Russian, test the reliability and validity of the Russian version and compare the scaling assumptions, reliability, and validity of the English, Spanish and Russian versions.
Materials/Methods:
GSK1210151A The development of a Russian version of the Quality of Life-Rheumatoid Arthritis Scale (QOL-RA Scale) involved translating the English version of the instrument into Russian, linguistic adaptation, 50 face-to-face interviews with outpatients with definite rheumatoid arthritis (RA) and testing the reliability and validity.
Results: The QOL-RA Scale, an 8-item scale, took about 3 minutes to administer. Psychometric analysis revealed that the psychometric attributes of English, Spanish and Russian questionnaires are satisfactory.
Conclusions: The Russian version of the QOL-RA scale is a reliable and valid
measure of RA-specific QOL.”
“Obesity hypoventilation syndrome (OHS) is defined as a combination of obesity (body mass index = 30 kg/m2), daytime hypercapnia (partial arterial carbon dioxide concentration =45 mm Hg) and sleep-disordered breathing after ruling out other disorders that may cause alveolar hypoventilation. Through the prism of the International Classification of Functioning, OHS is a chronic condition associated with respiratory, metabolic, hormonal and learn more cardiovascular impairments, leading to a decrease in daily life activities, a lack PP2 of social participation and high risk of hospitalization and death. Despite its severity, OHS is largely underdiagnosed and the health-related costs are higher than those of apnoeic
or obese eucapnic patients. The present review discusses the definition, epidemiology, physiopathology and treatment modalities of OHS. Although nocturnal positive airway pressure therapies represent first-line treatment and are effective in improving patient outcomes, there is a need to offer combined treatment strategies and to assess the effect of multimodal therapeutic strategies on morbidity and mortality.”
“Purpose: To determine whether Rg1 inhibits H2O2-induced injury in human umbilical vein endothelial cells (HUVECs), an injury often regarded as a key early event in the development of atherosclerosis.
Methods: Cell viability of HUVECs treated with Rg1 and/or H2O2 was measured using 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay. Lactate dehydrogenase (LDH) release, lipid peroxidation, and reserved oxidase were detected using different available kits. The apoptosis pathway involved in the effect of Rg1 was also evaluated.
Results: Exposing HUVECs to 100 mu mol/L H2O2 significantly decreased cell viability (78.12 +/- 1.