Results. An interventional radiologist was called find more for and he was able to angiographically locate the source of bleeding and stem its source using coil embolization of the
lumbar artery.
Conclusion. Whenever there is bleeding from an inaccessible site, consultation with an interventional radiologist to perform an intraoperative coil embolization of the injured vessel should be done especially if a resort to an anterior abdominal approach would permit uncontrolled bleeding.”
“Helicobacter pylori (H. pylori) infection, the main cause of chronic gastritis, increases gastric cancer risk. Antibiotics-based H. pylori eradication treatment is 90 % effective. However, it is expensive and causes side effects and antibiotic resistance. Lactic acid bacteria (LAB) could present a
low-cost, large-scale alternative solution to prevent or decrease H. pylori colonization.
This work aimed to study the inhibitory effects of LAB strains on the growth and pathogenic activity of H. pylori stains. To this end, we have selected the most virulent H. pylori strains (out of 20 mucosal antral biopsies) regarding cellular GSK872 vacuolization and induction of apoptosis/necrosis.
The selection of H. pylori pathogenic strains (clinically pre-isolated) were based on their impact of VacA activities on Hep-2 cell line, induction of apoptosis and necrosis in Caco-2 cell line. The Inhibitory effect of LAB strains on the invasion was carried out using the Caco-2 and Hela cell lines, where, PARP inhibitor they were co-cultured with the pathogenic H. pylori in the presence or absence of LAB extracts. The effect of LAB extracts on TNF-alpha secretion which induced by H. pylori-LPS was carried out by RT-qPCR.
L. bulgaricus DSMZ 20080, L. acidophilus and L. plantarum (studied previously and reported as high antioxidant candidate strains) showed the highest anti-pylori activities with inhibition ranged from 51.46 to 88.19 %, they preventing the adhesion, invasion and DNA fragmentation of cell lines. In addition, they could reduce the TNF-alpha expression by 62.13 %.
LAB extracts could inhibit the bacterial adhesion and invasion, gastric inflammation and DNA fragmentation induced by Helicobacter
pylori.”
“Malignant tumours of the vulvar soft tissue are very uncommon. When localized in the Bartholin’s gland area these tumours can be mistaken for benign lesions, leading to a delayed diagnosis.
A 52-year-old woman presenting with a vulvar nodule, which was diagnosed as a Bartholin’s gland cyst and was referred to the hospital for surgical excision of the lesion. Pathologist report informed of a 6 cm diameter leiomyosarcoma of the vulva with compromised resection margins; extension studies did not suggest any additional lesions and radical hemivulvectomy with ipsilateral inguinal lymphadenectomy was performed. The patient subsequently received radiotherapy and chemotherapy. Twelve months later, a local recurrence was diagnosed and was removed surgically.