Appropriate choice of antimicrobial agents and optimal duration of therapy in neonates with suspected or culture-proven sepsis is essential in order to prevent serious consequences. Moreover the establishment of an antibiotic stewardship programme in the NICUs is the best way of ensuring

neonatal infections remain treatable while efforts are made for the developing of optimal antibiotic prescribing.”
“”"Anatomical Characters of the Leaf and Stem of Piper mikanianum (Kunth) Steud., Piperaceae. The genus Piper L. (Piperaceae) is found in tropical and subtropical regions, and it includes several species of interest in folk medicine, such as Piper mikanianum (Kunth) Steud. Commonly known as “”pariparoba”" or “”jaborandi”" in Portuguese, this plant is considered antiseptic, hepatoprotective and emmenagogue. This work has investigated the leaf and stem anatomy of this potential vegetal drug, in order selleck compound to establish structural characters for microscopic identification and for

differentiating from other species of the genus. Mature leaves and young stems were fixed, either sectioned by free-hand or embedded in glycol methacrylate and sectioned by microtome, and then stained. The leaf has uniseriate epidermis, tetracytic selleckchem stomata exclusively on the abaxial side, glandular and non-glandular trichomes, parenchymatic sub-epidermal layers, dorsiventral mesophyll, secretory cells and calcium oxalate raphides. The midrib and petiole show collateral vascular bundles. In the caulinar level

analysed, the epidermis remains and the phellogen has peripheral installation. There are collateral vascular bundles arranged in two rings, the external one in the vascular cylinder and the internal one in the pith. In the perimedular zone, it occurs a sinuous sclerenchymatic sheath and a canal is present in the central region.”
“Objective: This study reports on an experience following contact by a large number of newborn babies with a nurse infected by active tuberculosis (TB). Methods: A large number of newborn MK-8776 ic50 babies were checked for possible contact with Mycobacterium tuberculosis (MTB) using interferon-gamma tests (IGTs) to determine specific treatment. Results: One hundred and seven infants showed a positive IGT positive and were not affected by active TB. All were treated with anti-tubercular drugs and were followed-up for 1 year. None of the infants developed active TB and all infants showed normal tuberculin skin tests and chest-x-rays, as well as IGT results at the end of treatment. Conclusions: Our experience suggests that newborns are at low risk of infection after contact with a nurse with active TB. IGTs can be used to assess possible contact with MTB and to determine a reduced number of infants to treat.”
“The present study was designed to investigate the antiulcer activity of ethyl acetate extract of Citrus decumana (grapefruit) peels.